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Phase I study of topotecan (T) with carboplatin (C) alternating with paclitaxel (P) via 3 hour infusion with carboplatin (C) in treatment of newly diagnosed ovarian cancer (OC)

✍ Scribed by A.N. Gordon; M. Doherty; K.C. Hancock; M. Messing; C.M. Matthews; M. Teneriello; T. Patton; C.A. Stringer

Book ID: 117667892
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 118 KB
Volume: 35
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(99)81353-7

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## BACKGROUND. The combination of paclitaxel and carboplatin is widely used in the treatment of patients with advanced nonsmall cell lung carcinoma. In this Phase I/II study the authors evaluated the feasibility, toxicity, and efficacy of adding a third active antineoplastic agent, gemcitabine, to