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Phase I Study of the Farnesyltransferase Inhibitor Lonafarnib with Paclitaxel in Solid Tumors

✍ Scribed by Khuri, F. R.

Book ID: 124058240
Publisher: American Association for Cancer Research
Year: 2004
Tongue: English
Weight: 221 KB
Volume: 10
Category: Article
ISSN: 1078-0432
DOI: 10.1158/1078-0432.CCR-03-0412

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## Abstract ## BACKGROUND The authors evaluated the safety, tolerability, and efficacy of treatment using lonafarnib, a novel farnesyltransferase inhibitor (FTI), in combination with paclitaxel in patients with metastatic (Stage IIIB/V), taxane‐refractory/resistant nonsmall cell lung carcinoma (NS

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