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Phase I study of oral JM216 given twice daily

โœ Scribed by P. Beale; F. Raynaud; J. Hanwell; C. Berry; S. Moore; D. Odell; I. Judson


Publisher
Springer
Year
1998
Tongue
English
Weight
303 KB
Volume
42
Category
Article
ISSN
0344-5704

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Phase I study of oral spirogermanium
โœ Jimmie Harvey; Molly McFadden; Frederick P. Smith; Lucien Joubert; Philip S. Sch ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer US ๐ŸŒ English โš– 241 KB

Thirty-three patients with advanced malignancy were treated with oral spirogermanium in a Phase I study to determine a maximum tolerated dose. Patients were entered in the study at doses of 100, 200, and 300 milligrams daily. The dose-limiting toxicity was gastrointestinal with moderate nausea and v