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Phase I study of olaparib in combination with liposomal doxorubicin in patients with advanced solid tumours

✍ Scribed by Del Conte, G; Sessa, C; von Moos, R; Viganò, L; Digena, T; Locatelli, A; Gallerani, E; Fasolo, A; Tessari, A; Cathomas, R; Gianni, L

Book ID
126597159
Publisher
Nature Publishing Group
Year
2014
Tongue
English
Weight
299 KB
Volume
111
Category
Article
ISSN
0007-0920

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## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and gemcitabine have single‐agent activity in breast and ovarian carcinoma patients. We conducted a Phase I trial to evaluate the maximum tolerated dose (MTD) and toxicities of this combination in patients with advanced malignancie