Phase I study of irinotecan and cisplatin with concurrent split-course radiotherapy in limited-disease small-cell lung cancer
โ Scribed by M Oka; M Fukuda; M Kuba; M Ichiki; T Rikimaru; H Soda; J Tsurutani; Y Nakamura; S Kawabata; K Nakatomi; F Narasaki; S Nagashima; H Takatani; M Fukuda; A Kinoshita; S Kohno
- Book ID
- 117659024
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 109 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0959-8049
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## Abstract ## BACKGROUND. A Phase II trial of irinotecan and cisplatin (IP) with early concurrent radiotherapy was performed in limitedโdisease smallโcell lung cancer (LDโSCLC) to evaluate the efficacy and toxicity. ## METHODS. For untreated LDโSCLC patients, irinotecan (60 mg/m^2^, Days 1, 8,
## Abstract ## BACKGROUND. The purpose was to determine the efficacy and toxicity of irinotecan and cisplatin with concurrent splitโcourse thoracic radiotherapy (TRT) in locally advanced nonsmallโcell lung cancer. ## METHODS. Fifty patients fulfilling the following eligibility criteria were enro