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Phase I Dose Escalation Trial of Vandetanib With Fractionated Radiosurgery in Patients With Recurrent Malignant Gliomas

✍ Scribed by Emma C. Fields; Denise Damek; Laurie E. Gaspar; Arthur K. Liu; Brian D. Kavanagh; Allen Waziri; Kevin Lillehei; Changhu Chen

Book ID
118455304
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
387 KB
Volume
82
Category
Article
ISSN
0360-3016

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## Abstract ## BACKGROUND Although temozolomide is active against recurrent malignant glioma, responses in many patients are modest and short‐lived. Temozolomide may prove more effective in combination with other agents. Therefore, combination oral chemotherapy for these patients is a particularly