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Phase I clinical trial of gemcitabine given as an intravenous bolus on 5 consecutive days

โœ Scribed by O'Rourke, T.J.; Brown, T.D.; Havlin, K.; Kuhn, J.G.; Craig, J.B.; Burris, H.A.; Satterlee, W.G.; Tarassoff, P.G.; Von Hoff, D.D.


Book ID
123058049
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
275 KB
Volume
30
Category
Article
ISSN
0959-8049

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A Phase I clinical trial of ixabepilone
โœ Sen H. Zhuang; Manish Agrawal; Maureen Edgerly; Susan Bakke; Herb Kotz; Paul Tha ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 86 KB

## Abstract ## BACKGROUND The epothilones are a novel class of microtubuleโ€stabilizing agents. Ixabepilone (BMSโ€247550; NSC 710428) is a semisynthetic analog of the natural product epothilone B. The authors conducted a Phase I study by administering ixabepilone to patients as a 1โ€hour intravenous