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Phase I clinical and pharmacokinetic trial of docetaxel and irinotecan administered on a weekly schedule

✍ Scribed by Agustin A. Garcia; Mahesh Pujari; Susan Jeffers; Syma Iqbal; Heinz-Josef Lenz; Paul Beringer; Stan Louie

Publisher
Springer
Year
2005
Tongue
English
Weight
241 KB
Volume
56
Category
Article
ISSN
0344-5704

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Phase I clinical trial of weekly combine
Phase I clinical trial of weekly combined paclitaxel plus docetaxel in patients with solid tumors
✍ Jacob Lokich πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 70 KB πŸ‘ 2 views

A Phase I and feasibility study of combined docetaxel (D) plus paclitaxel (P) was undertaken to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) for each analogue delivered concomitantly on a weekly schedule. ## METHODS. Patients were accrued in 3-6 patient cohorts to P