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Phase I and pharmacokinetic trial of carboplatin and albumin-bound paclitaxel, ABI-007 (Abraxane®) on three treatment schedules in patients with solid tumors

✍ Scribed by Thomas E. Stinchcombe; Mark A. Socinski; Christine M. Walko; Bert H. O’Neil; Frances A. Collichio; Anastasia Ivanova; Hua Mu; Michael J. Hawkins; Richard M. Goldberg; Celeste Lindley; E. Claire Dees


Publisher
Springer
Year
2007
Tongue
English
Weight
388 KB
Volume
60
Category
Article
ISSN
0344-5704

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## Background: Ifosfamide and paclitaxel are antineoplastic agents with broad activity and with different mechanisms of action. a phase i trial was conducted to determine the maximum tolerated dose and associated toxicities of these agents when used in combination. ## Methods: Patients with refra