๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Phase I and pharmacokinetic study of LY309887: a specific inhibitor of purine biosynthesis

โœ Scribed by Daniel R. Budman; Robert Johnson; Barbara Barile; Ronald R. Bowsher; Vincent Vinciguerra; Steven L. Allen; Jonathan Kolitz; Steven C. Ernest; Willi Kreis; Peter Zervos; Jackie Walling


Publisher
Springer
Year
2001
Tongue
English
Weight
131 KB
Volume
47
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Phase I study of methylacetylenic putres
โœ Michael A. Cornbleet; Andrew Kingsnorth; Guy P. Tell; Klaus D. Haegele; Anne-Mar ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 437 KB

In a phase I clinical trial, nine patients with advanced malignancies not amenable to alternative therapy received c~-methyl-~-acetylenic putrescine (MAP), an enzyme-activated, irreversible inhibitor of ornithine decarboxylase (ODC). MAP was given orally in increasing doses to successive groups of t