Phase behaviour of aqueous systems of enzymatically modified phosphatidylcholines with one hexadecyl and one hexyl or octyl chain
✍ Scribed by I. Svensson; P. Adlercreutz; B. Mattiasson; Y. Miesiz; K. Larsson
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 200 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0009-3084
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✦ Synopsis
Phosphatidylcholines composed of a hexadecyl chain in the 2-position and a hexyl or octyl chain in the l-position (C6CI6PC or CsC~6PC) were prepared from dipalmitoyiphosphatidylcholine by lipase-catalyzed transesterification; the aqueous phase properties of the products were examined. In the CsCl6PC-water system, a lamellar liquid-crystalline phase was dominant. Like all long-chain phosphatidylcholines studied earlier, a liposomal dispersion was formed in the presence of excess water. In the C6C26PC system, a new type of phase behaviour was observed; at high water content, an L 3 phase was formed.