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Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases

✍ Scribed by Raffaele Addeo; Carmine De Rosa; Vincenzo Faiola; Luigi Leo; Gregorio Cennamo; Liliana Montella; Rosario Guarrasi; Bruno Vincenzi; Michele Caraglia; Salvatore Del Prete


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
112 KB
Volume
113
Category
Article
ISSN
0008-543X

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## Abstract ## BACKGROUND. This randomized pilot trial investigated whether primary chemotherapy was feasible in terms of efficacy, survival, toxicity profile, and quality of life compared with whole‐brain radiotherapy (WBRT) given first in chemotherapy‐naive patients nonsmall cell lung cancer (NS