Phase 2 Study of Pegylated Liposomal Doxorubicin, Vincristine, Decreased-Frequency Dexamethasone, and Thalidomide in Newly Diagnosed and Relapsed-Refractory Multiple Myeloma
โ Scribed by Hussein, Mohamad A.; Baz, Rachid; Srkalovic, Gordan; Agrawal, Neeraj; Suppiah, Revathi; Hsi, Eric; Andresen, Steven; Karam, Mary Ann; Reed, Janice; Faiman, Beth
- Book ID
- 123321602
- Publisher
- Mayo Clinic
- Year
- 2006
- Tongue
- English
- Weight
- 97 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0025-6196
- DOI
- 10.4065/81.7.889
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In patients with multiple myeloma, there is preclinical justification to combine arsenic trioxide (ATO and As 2 O 3 ) with DVd (Doxil TM , vincristine, and dexamethasone) for newly diagnosed patients. Eleven patients on this phase II trial received 0.15 mg/kg of ATO for five consecutive days followe