Childhood immune thrombocytopenia (ITP) has a favorable outcome in most cases but severe bleeding may occur, mostly in children with very low platelet counts. Although first-line therapies are well defined, management of refractory ITP is not consensual. Vinblastine (VBL) is one second-line treatmen
β¦ LIBER β¦
Phase 1 study of PTK787/ZK 222584, a small molecule tyrosine kinase receptor inhibitor, for the treatment of acute myeloid leukemia and myelodysplastic syndrome
β Scribed by Roboz, G J; Giles, F J; List, A F; Cortes, J E; Carlin, R; Kowalski, M; Bilic, S; Masson, E; Rosamilia, M; Schuster, M W
- Book ID
- 110056732
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 120 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0887-6924
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Combination decitabine, arsenic trioxide
β
John S. Welch; Jeffery M. Klco; Feng Gao; Elizabeth Procknow; Geoffery L. Uy; Ke
π
Article
π
2011
π
John Wiley and Sons
π
English
β 774 KB
A phase 1-2 study of a farnesyltransfera
β
Elias Jabbour; Hagop Kantarjian; Farhad Ravandi; Guillermo Garcia-Manero; Zeev E
π
Article
π
2010
π
John Wiley and Sons
π
English
β 221 KB
π 1 views
## Abstract ## BACKGROUND: The authors conducted a phase 1/2 study of tipifarnib in combination with idarubicin and cytarabine (IA) in 95 patients with previously untreated acute myeloid leukemia (AML) or highβrisk myelodysplastic syndrome. ## METHODS: Induction consisted of idarubicin 12 mg/m^2