A phase 2 study of the oral mammalian ta
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Brian M. Slomovitz; Karen H. Lu; Taren Johnston; Robert L. Coleman; Mark Munsell
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Article
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2010
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John Wiley and Sons
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English
β 118 KB
π 1 views
## Abstract ## BACKGROUND: Dysregulation of phosphatase and tensin homolog (PTEN) and the gene that encodes the p110Ξ± catalytic subunit of phosphatidylinositolβ3βkinase (PI3K), PIK3CA, are the most common mutations in endometrial carcinoma (EC). Loss of PTEN or activation of PIK3CA results in cons