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Pharmacotherapy of bipolar disorder: the role of atypical antipsychotics and experimental strategies

✍ Scribed by Gin S. Malhi; Michael Berk

Book ID: 102264413
Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 72 KB
Volume: 17
Category: Article
ISSN: 0885-6222
DOI: 10.1002/hup.437

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✦ Synopsis

Abstract

Bipolar disorder, despite being a common and debilitating illness, has remarkably few pharmacological therapeutic options, the majority of which, with the exception of lithium, have been borrowed from other medical indications. Furthermore the quantity and quality of controlled clinical data are considerably smaller than in conditions of comparable severity and frequency. Not surprisingly, the clinical outcome of bipolar disorder is frequently suboptimal.

Fortunately there are a growing number of novel therapeutic options for its treatment such as atypical antipsychotics, calcium channel blockers and omega‐3 fatty acids. This paper summarizes some of the data regarding these ‘experimental’ therapeutic options, focusing principally on atypical antipsychotics as these are now widely prescribed in the management of bipolar disorder. Copyright © 2002 John Wiley & Sons, Ltd.

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