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Pharmacology of [Tyr1]nociceptin analogs: receptor binding and bioassay studies

โœ Scribed by K. Varani; A. Rizzi; G. Calo; R. Bigoni; G. Toth; R. Guerrini; S. Gessi; S. Salvadori; P.A. Borea; D. Regoli


Book ID
105878480
Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
126 KB
Volume
360
Category
Article
ISSN
0028-1298

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โœ Sharon R. Letchworth; John P. Mathis; Grace C. Rossi; Richard J. Bodnar; Gavril ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 535 KB

The endogenous ligand for the orphan opioid receptor, orphanin FQ/nociceptin (OFQ), has recently been characterized. The OFQ peptide sequence contains paired basic amino acids, suggesting the possibility of posttranslational processing to a peptide containing the first 11 amino acids of the OFQ pept