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Pharmacology of the receptors for the phorbol ester tumor promoters: Multiple receptors with different biochemical properties

✍ Scribed by Marcelo G Kazanietz; Marı́a J Caloca; Pilar Eroles; Teruhiko Fujii; Marı́a L Garcı́a-Bermejo; Muredach Reilly; HongBin Wang


Book ID
113992449
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
575 KB
Volume
60
Category
Article
ISSN
0006-2952

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In addition to the well-characterized interaction with classical and novel protein kinase C (PKC) isozymes, the phorbol ester tumor promoters bind to other receptors lacking kinase activity. Among these novel phorbol ester receptors, two families of proteins may play a role in the regulation of cell