The seven serotypes of botulinum toxin (BTX) produced by Clostridium botulinum exert their paralytic effect by inhibiting acetylcholine release at the neuromuscular junction. Each of these zinc endopeptidases cleaves one or more proteins involved in vesicle transport and membrane fusion. The extent
โฆ LIBER โฆ
Pharmacology and immunology of botulinum toxin serotypes
โ Scribed by Aoki, K. R.
- Book ID
- 113012282
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 229 KB
- Volume
- 248
- Category
- Article
- ISSN
- 0340-5354
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Previous studies in this laboratory had mapped the immune recognition profile of the regions recognized antibodies (Abs) and by T cells on the protective H C domain (Cterminal fragment corresponding to residues 855-1296 of the heavy chain) of botulinum neurotoxin serotype A (BoNT/A). The localizatio