✦ LIBER ✦
Pharmacological studies of Striga senegalensis Benth (Scrophulariaceae) as an abortifacient
✍ Scribed by M. K. Choudhury; A. L. Phillips; A. Mustapha
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 64 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
The methanol extract of Striga senegalensis Benth (Scrophulariaceae) was investigated on isolated rat uterus. Acetylcholine and the methanol extract of the plant produced dose related contractions of smooth muscle of the isolated rat uterus in vitro. Atropine in doses of 2 Â 10 À2 to 32 Â 10 À2 mg/mL antagonized dose dependently the contraction of the isolated rat uterus produced by both acetylcholine (1.6 Â 10 À1 mg/mL) and the methanol extract (160 mg/mL).