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Pharmacological inhibition of noradrenergic system impairs a spatial decision-making task in rats

✍ Scribed by Amemiya, Seiichiro; Noji, Takumasa; Kubota, Natsuko; Nishijima, Takeshi; Kita, Ichiro

Book ID
122655156
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
107 KB
Volume
71
Category
Article
ISSN
0168-0102

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Deficits in decision-making have been repeatedly observed in various psychiatric disorders (i.e. ADHD, Pathological Gambling, Mania, OCD and Substance Abuse) as well as in frontal lobe patients. Such decision-making deficits are often assessed using the Iowa Gambling task (IGT) [1]. The IGT represen