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Pharmacological evidence for cardiac muscarinic receptor subtypes

✍ Scribed by C. Chassaing; G. Dureng; J. Baissat; P. Duchêne-Marullaz

Book ID
118340392
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
378 KB
Volume
35
Category
Article
ISSN
0024-3205

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Equilibrium binding assays support four (M 1 -M 4 ) and molecular cloning studies have identified five (m1-m5) muscarinic receptor subtypes in the brain and peripheral tissues. However, the overlapping affinities of virtually all of the available muscarinic antagonists have permitted the unambiguous