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Pharmacological evidence for a presynaptic action of venoms from Bothrops insularis (jararaca ilhoa) and Bothrops neuwiedi (jararaca pintada)

✍ Scribed by Léa Rodrigues-Simioni; Stella R Zamunér; José C Cogo; Caroline R Borja-Oliveira; Júlia Prado-Franceschi; Maria Alice da Cruz-Höfling; Alexandre P Corrado


Book ID
116921010
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
221 KB
Volume
43
Category
Article
ISSN
0041-0101

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## Abstract Pyroglutamyl proline‐rich oligopeptides, present in the venom of the pit viper __Bothrops jararaca__ (__Bj__‐PROs), are the first described naturally occurring inhibitors of the angiotensin I‐converting enzyme (ACE). The inhibition of ACE by the decapeptide __Bj__‐PRO‐10c (Bj‐PROs was c