Pharmacological evidence for a correlation between hippocampal CA1 cell damage and hyperlocomotion following global cerebral ischemia in gerbils

Green tea polyphenol (–)-epigallocatechi

Green tea polyphenol (–)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia

✍ Jong-Wan Park; Young-Ho Jang; Jin-Mo Kim; Hyung Lee; Weon-Kyun Park; Man-Bin Lim 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 402 KB

## Abstract Previous studies have demonstrated that (–)‐epigallocatechin gallate (EGCG), a green tea polyphenol, protects against ischemia and reperfusion‐induced injury in many organ systems. Here, we test the hypothesis that part of EGCG's neuroprotective effects may involve a modulation of matri