Pharmacological considerations in high-dose chemotherapy
β Scribed by Yasutsuna Sasaki
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 84 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0344-5704
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## Abstract Carboplatin has been reported to cause acute renal failure when administered in high doses to adult patients. We report a 4 1/2βyearβold girl who was treated with highβdose carboplatin for metastatic parameningeal embryonal rhabdomyosarcoma. Acute renal failure developed followed by a s
The role of high dose chemotherapy in the treatment of solid tumors is a subject of robust debate. Opinions range from the adoption of high dose chemotherapy with hematopoietic progenitor support as standard therapy for a number of solid tumors to the view that the application of such expensive and
## BACKGROUND. High dose chemotherapy (HDC) with hematopoietic stem cell support is an increasingly important strategy in the management of advanced cancer. Early Phase II studies and the development of peripheral blood stem cell support to enable safe and tolerable myeloablative chemotherapy has