✦ LIBER ✦

Pharmacological characterisation of the GlyT-1 glycine transporter using two novel radioligands

✍ Scribed by Hugh J. Herdon; Jennifer C. Roberts; Steve Coulton; Rod A. Porter

Book ID: 116785494
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 939 KB
Volume: 59
Category: Article
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2010.07.023

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Amino-terminal isoforms of the human gly

Amino-terminal isoforms of the human glycine transporter GlyT1 exhibit similar pharmacology

✍ John T. Durkin; Chrysanthe M. Spais; Justin Schreiber; Karla Kopec; Sheryl L. Me 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 636 KB

Novel inhibitors of the type 1 transport

Novel inhibitors of the type 1 transporter for glycine (GlyT1) as antipsychotic agents

✍ Lowe III, John A 📂 Article 📅 2005 🏛 Informa plc 🌐 English ⚖ 127 KB

Molecular identification and characteris

Molecular identification and characterisation of the glycine transporter (GLYT1) and the glutamine/glutamate transporter (ASCT2) in the rat lens

✍ Julie Lim; Karen A. Lorentzen; Joerg Kistler; Paul J. Donaldson 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 741 KB

Pharmacological assessment of the role o

Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes

✍ H.J Herdon; F.M Godfrey; A.M Brown; S Coulton; J.R Evans; W.J Cairns 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 158 KB

P43 Functional characterisation of the n

P43 Functional characterisation of the novel CLC-1 variants C179Y and A529V using Two-Electrode-Voltage-Clamp and review of ClC-1 structure–function

✍ Suetterlin, K.; Hanna, M.G.; Männikkö, R. 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 55 KB

Radiosynthesis of [5-[11C]methanesulfony

Radiosynthesis of [5-[11C]methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-[5-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindol-2-yl]-methanone ([11C]RO5013853), a novel PET tracer for the glycine transporter type I (GlyT1)

✍ Emmanuel Pinard; Serge Burner; Philipp Cueni; Thomas Hartung; Roger D. Norcross; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 300 KB

The glycine transporter type 1 (GlyT1) has emerged as a key novel target for the treatment of schizophrenia. We have recently discovered and developed [^11^C]RO5013853 as a novel positron emission tomography tracer for GlyT1 for which a reliable five‐step synthetic route was established. The incorpo