Pharmacological and toxicological investigations on Foeniculum vulgare dried fruit extract in experimental animals
✍ Scribed by M. O. M. Tanira; A. H. Shah; A. Mohsin; A. M. Ageel; S. Qureshi
- Book ID
- 101285458
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 387 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
The ethanol extract of the dried ripe fruit of Foeniculum vulgare (500 mg/kg) was tested for diuretic, analgesic, antipyretic, antimicrobial, cytotoxic activities and its effect on bile secretion in rats. Also, the acute toxicity after 0.5, 1 and 3 gkg was investigated in mice. The extract showed diuretic, analgesic, antipyretic activities and it enhanced bile secretion. As an antimicrobial agent, the extract inhibited the growth of Staphylococcus aweus and Bacillus subtilis and showed a marked mitodepressive effect. At a dose of 3 fig, it caused piloerection and it depressed locomotor activity but caused no deaths when administered acutely to mice.