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Pharmacological and biochemical characterization of the beta-adrenergic signal transduction pathway in different segments of the respiratory tract

✍ Scribed by Getu Abraham; Claudia Kottke; Stefan Dhein; Fritz Rupert Ungemach


Book ID
113993665
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
321 KB
Volume
66
Category
Article
ISSN
0006-2952

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In examining the signaling transduction pathway of adrenoceptors in oligodendrocyte progenitors, we have found that stimulation of ␣ 1 -adrenoceptors with norepinephrine (NE), in the presence of 3 M propranolol, increased the activity of mitogen-activated protein kinases (MAPKs). This stimulation wa