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Pharmacological and biochemical characteristics of learning deficit induced by ibotenic acid lesion of the frontal cortex in rats

✍ Scribed by C. Hara; A. Mitani; S. Masuda; K. Kataoka; N. Ogawa


Publisher
Springer
Year
1989
Tongue
English
Weight
64 KB
Volume
1
Category
Article
ISSN
1435-1463

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## Abstract Symptoms in the early stages of Huntington's disease (HD) are assumed to reflect basal ganglia circuit dysfunction secondary to degeneration of striatal projections to the external segment of the globus pallidus (GPe). The hypothesis that GPe lesion would ameliorate HD symptoms by β€œnorm