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Pharmacologic Resuscitation Promotes Survival and Attenuates Hemorrhage-Induced Activation of Extracellular Signal-Regulated Kinase 1/2

โœ Scribed by Eugene Y. Fukudome; Ashley R. Kochanek; Yongqing Li; Eleanor J. Smith; Baoling Liu; Tareq Kheirbek; Jennifer Lu; Kyuseok Kim; Kristopher Hamwi; George C. Velmahos; Hasan B. Alam


Book ID
116706440
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
396 KB
Volume
163
Category
Article
ISSN
0022-4804

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## Abstract Early growth response gene (__Egrโ€1__) is a stress response gene activated by various forms of stress and growth factor signaling. We report that supraphysiologic concentrations of O~2~ (hyperoxia) induced Egrโ€1 mRNA and protein expression in cultured alveolar epithelial cells, as well