Pharmacologic characteristics of a new calcium antagonist, manidipine: Beneficial effects on renal circulation and vascular changes

Effects of benidipine hydrochloride (Con

Effects of benidipine hydrochloride (Coniel®), a new calcium antagonist, on the cardiac output, regional blood flow and vascular resistance in conscious, spontaneously hypertensive rats

✍ Hideyoshi Harashima; Hiroshi Kiwada; Jirou Kajita; Satoshi Kobayashi 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 453 KB 👁 2 views

## Abstract Benidipine hydrochloride is a calcium antagonist with a 1,4‐dihydropyridine derivative structure, and exhibits long‐lasting antihypertensive effects by inhibiting the voltagedependent Ca^2+^ channels. This study was undertaken to examine the effect of benidipine on central haemodynamics