Circadian variations in the pharmacokine
β
Qing-Ri Cao; Tae-Wan Kim; Jun Shik Choi; Beom-Jin Lee
π
Article
π
2005
π
John Wiley and Sons
π
English
β 129 KB
π 2 views
## Abstract Circadian variations in the pharmacokinetics, tissue distribution and urinary excretion of nifedipine were examined in fasted rats after administering a single oral dose at three different dosing times (08:00 am, 16:00 pm, 00:00 am). The plasma concentrations, the areas under the plasma