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Pharmacokinetics, tissue distribution and bioavailability of clozapine solid lipid nanoparticles after intravenous and intraduodenal administration

โœ Scribed by Kopparam Manjunath; Vobalaboina Venkateswarlu


Book ID
113690980
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
186 KB
Volume
107
Category
Article
ISSN
0168-3659

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โœ Zara, Gian Paolo (author);Bargoni, Alessandro (author);Cavalli, Roberta (author) ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 143 KB

Idarubicin-loaded solid lipid nanoparticles (IDA-SLN) and idarubicin in solution were prepared and the two formulations were administered to rats, either by the duodenal route or intravenously (iv). The aim of this research was to study whether the bioavailability of idarubicin can be improved by ad