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Pharmacokinetics of tiopronin after repeated oral administration in rheumatoid arthritis

✍ Scribed by P. Gillet; C. Gavriloff; B. Hercelin; MF Salles; A. Nicolas; P. Netter

Book ID
115274106
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
129 KB
Volume
9
Category
Article
ISSN
0767-3981

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## Abstract ## Objective There is evidence supporting a therapeutic range for methotrexate polyglutamate (MTXGlu) concentrations in the treatment of rheumatoid arthritis (RA). Knowledge of the pharmacokinetics of MTXGlu~1–5~ is required for optimal timing of blood sampling. The aim of this study w