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Pharmacokinetics of the three radioiodinated dopamine D2 receptor ligands [123I]IBF, [123I]epidepride and [123I]2′-ISP in nonhuman primates

✍ Scribed by Baldwin, Ronald M.; Zea-Ponce, Yolanda; Zoghbi, Sami S.; Al-Tikriti, Mohammed S.; Seibyl, John P.; Sybirska, Elzbieta H.; Malison, Robert T.; Laruelle, Marc; Charney, Dennis S.; Hoffer, Paul B.

Book ID
123580486
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
902 KB
Volume
21
Category
Article
ISSN
0969-8051

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## Abstract We used the reversibly binding D2 dopamine receptor radioligand [^123^I]IBZM (iodobenzamide) to test whether the endogenous neurotransmitter dopamine competes in vivo for radiotracer binding measured with single photon emission computed tomography (SPECT). In a series of nonhuman primat