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Pharmacokinetics of the S- and R-enantiomers of aminoglutethimide in saliva of breast cancer patients: Correlations with plasma

✍ Scribed by I. A. Alshowaier; A. El-Yazigi; A. Ezzat; A. El-Warith; P. J. Nicholls


Book ID
118111035
Publisher
Pharmaceutical Press
Year
1998
Tongue
English
Weight
104 KB
Volume
50
Category
Article
ISSN
2042-7158

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The pharmacokinetics of the optical enantiomers of warfarin (R-warfarin and S-warfarin) were investigated in patients treated for breast cancer with aminoglutethimide (AG). The patients received 125 mg AG b.i.d. (i.e., low-dosage regimen); 250 mg AG q.i.d. together with cortisone acetate (i.e. high-