Methyl t-butyl ether (MTBE) is a commonly used octane booster in gasoline. This study examines the pharmacokinetics and disposition of MTBE in Fischer-344 rats after i.v., oral, dermal and inhalation routes of administration. Groups of male and female rats were given single i.v. (40 mg kg -1 ), oral
โฆ LIBER โฆ
Pharmacokinetics of tertiary butyl alcohol in male and female Fischer 344 rats
โ Scribed by Torka S. Poet; John L. Valentine; Susan J. Borghoff
- Book ID
- 119539290
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 690 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0378-4274
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The purpose of this study was to evaluate whether repeated 6-h exposure (65 exposures over a 14- week period) of male and female Fischer-344 rats (n = 12 rats/sex/concentration) to ethyl tertiary-butyl ether (ETBE) atmospheres at 500, 1750, or 5000 ppm would result in neurotoxicity. Neurotoxicity wa
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