Uridine pharmacokinetics in cancer patie
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Thomas C. K. Chan; Maurie Markman; Craig E. Pfeifle; Raymond Taetle; Ian Abramso
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Article
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1988
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Springer
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English
โ 408 KB
The availability of uridine can alter the sensitivity of tumor cells to antimetabolites such as N-phosphonacetyl-L-aspartic acid (PALA) and acivicin by virtue of the cell's ability to salvage preformed metabolites from its environment. We investigated the pharmacokinetics of physiologically relevant