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Pharmacokinetics of sunitinib malate in subjects with hepatic impairment

โœ Scribed by Carlo L. Bello; May Garrett; Laurie Sherman; John Smeraglia; Bob Ryan; Melvin Toh

Publisher
Springer
Year
2010
Tongue
English
Weight
239 KB
Volume
66
Category
Article
ISSN
0344-5704

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The single-dose pharmacokinetics of nefazodone (NEF) and its metabolites hydroxynefazodone (HO-NEF) and m-chlorophenylpiperazine (mCPP) were examined in 12 healthy younger subjects < 55 years of age (YNG), 12 elderly subjects > 65 years of age (ELD), 12 patients with biopsy proven hepatic cirrhosis