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Pharmacokinetics of sulfadimethoxine and sulfamethoxazole in combination with trimethoprim after intravenous administration to healthy and pneumonic pigs

✍ Scribed by M.J.B. MENGELERS; E.R. VAN GOGH; H.A. KUIPER; A. PIJPERS; J.H.M. VERHEIJDEN; A.S.J.P.A.M. VAN MIERT


Book ID
114744969
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
902 KB
Volume
18
Category
Article
ISSN
0140-7783

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✍ P. Lundborg; B. Abrahamsson; I. Wieselgren; M. Walter πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 302 KB

We have studied a controlled-release formulation containing metoprolol 100 mg and hydrochlorothiazide 12.5 mg. We compared the pharmacokinetics of both substances and the pharmacodynamics of metoprolol with those of a conventional combination tablet. The controlled-release formulation gave less vari