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Pharmacokinetics of slow-release preparations of sodium valproate

โœ Scribed by YASUKO YAMATOGI; HARUMI YOSHINAGA; EIJI OKA; SHUNSUKE OHTAHARA; SYOICHI YAMASHITA; KATSUSHI FURUNO; YUTAKA GOMITA


Book ID
118709229
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
239 KB
Volume
49
Category
Article
ISSN
1323-1316

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## Abstract The effect of food intake on the pharmacokinetics of DEPAKINEยฎ CHRONO 500 mg (Sanofi, France), a sustained release formulation containing 333 mg sodium valproate and 145 mg valproic acid, was studied in 12 young healthy female volunteers. Relative to fasting conditions (F), when the tab