Pharmacokinetics of reboxetine in healthy, elderly volunteers
✍ Scribed by J. F. Bergmann; J P Laneury; P. Duchene; J C Fleishaker; G. Houin; J -M Ségrestaa
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 585 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0378-7966
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The pharmacokinetics of reboxetine, a new antidepressant agent, were found to be close to linear in a crossover study comparing administration of single 2, 3, 4 and 5 mg capsule doses in 15 healthy male volunteers, and in the same study the capsules were bioequivalent to the proposed th
Reboxetine is a racemic mixture of FCE 22071 and FCE 21684 enantiomers. The pharmacokinetics of the enantiomers of reboxetine were observed to be linear in male healthy subjects (n = 6) after the administration of 1.5, 3, 4.5 mg dose of reboxetine as solutions. Kinetic analysis was based on chiral H
A single dose open labelled two-way randomized crossover study was used to assess the pharmacokinetics of diazepam from a controlled release capsule relative to standard release tablets in elderly volunteers. Eighteen volunteers received a single 15 mg controlled release capsule or a 5mg tablet t.i.
The pharmacokinetics of reboxetine have been investigated in 12 healthy male volunteers after a single 2mg dose of reboxetine and at steady state, following the last administration of a multiple-dose regimen (2mg twice a day for 54d). Reboxetine was analysed in plasma and urine samples collected up
The plasma and urine kinetics of rufloxacin were assessed in healthy volunteers after single (100, 200, 400 and 800 mg) and multiple (300 mg followed by 150 mg daily, Group 1, and 400 mg followed by 200 mg daily, Group 2) oral doses. The kinetics of a single oral dose of 800 mg was assessed in fasti