Objectives: To determine the effect of reduced hepatic function on the pharmacokinetics of minoxidil. The pharmacokinetics of antipyrine, lorazepam, and indocyanine green were included as indicators of hepatic function. Methods: Eight mild cirrhotics and eight healthy subjects received antipyrine (p
Pharmacokinetics of praziquantel in healthy volunteers and patients with schistosomiasis
โ Scribed by Mohammed El M. Mandour; Hamid El Turabi; Mamoun M.A. Homeida; Taha el Sadig; Hassan M. Ali; James L. Bennett; William J. Leahey; Dean W.G. Harron
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 553 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0035-9203
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## Abstract Selegiline is beneficial to Parkinsonian patients as an adjunct to levodopa therapy. A sensitive fluorimetric assay based on ibhibition of rat brain monoamine oxidaseโB (MAOโB) __in vitro__ has been developed to study the pharmacokinetics of selegiline. This method quantitates selegilin