The plasma and urine kinetics of rufloxacin were assessed in healthy volunteers after single (100, 200, 400 and 800 mg) and multiple (300 mg followed by 150 mg daily, Group 1, and 400 mg followed by 200 mg daily, Group 2) oral doses. The kinetics of a single oral dose of 800 mg was assessed in fasti
Pharmacokinetics of piroximone (MDL 19.205) in healthy volunteers
β Scribed by K. D. Haegele; G. G. Belz; T. T. Meinicke; P. J. Schechter
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 295 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0031-6970
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## Abstract Selegiline is beneficial to Parkinsonian patients as an adjunct to levodopa therapy. A sensitive fluorimetric assay based on ibhibition of rat brain monoamine oxidaseβB (MAOβB) __in vitro__ has been developed to study the pharmacokinetics of selegiline. This method quantitates selegilin