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Pharmacokinetics of orally administered pirfenidone in male and female beagles

โœ Scribed by M. L. Bruss; S. B. Margolin; S. N. Giri


Book ID
108884883
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
160 KB
Volume
27
Category
Article
ISSN
0140-7783

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Pharmacokinetics of orally administered
โœ M. Van Der Graaff; N. P. E. Vermeulen; P. Heij; J. K. Boeijinga; D. D. Breimer ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 375 KB ๐Ÿ‘ 2 views

Hexobarbital (HB) concentrations were determined in plasma and saliva of 8 healthy subjects, following oral administration of 500 mg HB-Na. Mean plasma half-lives were 3.2 k 0.1 h, and salivary half-lives 3.3 k 0.2 h. Mean plasma clearance was 22.9 k 2.3 1 h-'. There was a linear relationship betwee