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Pharmacokinetics of oral valacyclovir and acyclovir in late pregnancy

✍ Scribed by Debora F. Kimberlin; Stephen Weller; Richard J. Whitley; William W. Andrews; John C. Hauth; Fred Lakeman; Gerri Miller


Book ID
113985481
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
124 KB
Volume
179
Category
Article
ISSN
1097-6868

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## Abstract ## Background The efficacy of oral acyclovir, a purine nucleoside analogue with activity against human herpes viruses, is limited as a result of its low bioavailability. Valacyclovir, the L‐valyl ester of acyclovir, has been developed as a pro‐drug to improve the bioavailability. The a