Pharmacokinetics of nateglinide enantiomers and their metabolites in Goto-Kakizaki rats, a model for type 2 diabetes mellitus

Effects of long-term treatment with α-gl

Effects of long-term treatment with α-glucosidase inhibitor on the peripheral nerve function and structure in Goto-Kakizaki rats: a genetic model for Type 2 diabetes

✍ Ryuichi Wada; Motoi Koyama; Hiroki Mizukami; Hiroyuki Odaka; Hitoshi Ikeda; Soro 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 116 KB 👁 1 views

Background Continuous hyperglycemia is implicated in the pathogenesis of chronic diabetic complications. It is not well known, however, how and to what extent the development of neuropathy is inhibited by blood glucose control in subjects with Type 2 diabetes. We investigated therefore the effects o