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Pharmacokinetics of morphine and plasma concentrations of morphine-6-glucuronide following morphine administration to dogs

✍ Scribed by B. KUKANICH; B. D. X. LASCELLES; M. G. PAPICH


Book ID
108884932
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
108 KB
Volume
28
Category
Article
ISSN
0140-7783

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NASAL ADMINISTRATION OF MORPHINE-6-GLUCU
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The pharmacokinetics of morphine-6-glucuronide (M6G) after both intravenous dosing and nasal administration were studied in sheep. The nasal formulation consisted of M6G in combination with an absorption promoting delivery system in the form of chitosan. The mean half-life of M6G after intravenous a