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Pharmacokinetics of molsidomine and its active metabolite, linsidomine, in patients with liver cirrhosis.

✍ Scribed by O Spreux-Varoquaux; J Doll; C Dutot; N Grandjean; P Cordonnier; M Pays; J Andrieu; C Advenier

Book ID
117945152
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
517 KB
Volume
32
Category
Article
ISSN
0306-5251

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Pharmacokinetics of diacerein in patient
Pharmacokinetics of diacerein in patients with liver cirrhosis
✍ O. Magnard; K. Louchahi; M. Tod; O. Petitjean; P. Molinier; L. Berdah; G. Perret πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 388 KB πŸ‘ 1 views

The pharmacokinetics of diacerein following a single oral dose of 50 mg was studied in 12 healthy volunteers, 10 patients with a mild liver cirrhosis (Child Pugh's grade A), and 6 patients with a more severe liver cirrhosis (Child Pugh's grade B to C). Statistical analysis using a Kruskal-Wallis tes