Pharmacokinetics of mefloquine in the presence of primaquine
โ Scribed by J. Karbwang; K. Na Bangchang; A. Thanavibul; D. J. Back; D. Bunnag
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 200 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The disposition of primaquine (0.75 mg, 5 pC1) has been investigated in the isolated perfused rat liver (IPRL) preparation alone and concurrently with mefloquine. In both groups, primaquine concentrations declined exponentially. There were no significant differences between the respective groups in
The kinetics of a single oral dose of mefloquine given either alone or with ampicillin has been studied in 8 healthy Thai male volunteers. There was a significantly higher maximum whole blood mefloquine concentration after coadministration with ampicillin (1648 vs 1228 ng.ml-1), as well as a signifi